"I agree with you jarhead_h. If Jesse's goal is to put a permanent wedge between Cameron and John, the best way would be if she made it look like Cameron killed Riley.

But what should Cameron do? I think the only thing she could do is tell John what Jesse and Riley are doing. Then John would probably confront Riley and Riley would probably break down and confess. She might be able to convince him that she was pressured by Jesse so that might not end the relationship. But that would prevent Jesse from being able to turn John against Cameron. Cameron told him the truth when everyone else around him lied. He might trust her again. He might even come to the conclusion that a human girlfriend is impossible for him to have and he might turn to Cam. (ok, just having a shipper moment)."